Spectrophotometric determination of pyrimethamine (PYM) in pharmaceutical formulation using 1,2-naphthoquinone-4-sulfonate (NQS)
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منابع مشابه
Spectrophotometric Determination of Corticosteroids and Its Application in Pharmaceutical Formulation
A simple, sensitive and economically viable spectrophotometric method for the determination of corticosteroids (predinsolone {PSL}, dexamethasone {DEX}, prednisone {PS}, betamethasone sodium phosphate {BEP} and hydrocortisone {HYD} has been developed. The method involves the oxidation of corticosteroids by iron (III) and subsequent complexation of iron (II) with potassium hexacynoferrate (III),...
متن کاملSpectrophotometric determination of tiopronin using its catalytic reaction between sodium 1,2-naphthoquinone-4-sulfonate and hydroxyl ion.
A novel and simple spectrophotometric method for the determination of tiopronin with sodium 1,2-naphthoquinone-4-sulfonate (NQS) is established in this paper. The detailed mechanism is proposed and discussed. It is based on the fact that tiopronin can catalyze the reaction between sodium 1,2-naphthoquinone-4-sulfonate and hydroxyl ion to form 2-hydroxy-1,4-naphthoquinone in a buffer solution of...
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1,2-Naphthoquinone-4-Sulphonic Acid Sodium Salt (NQS) as an Analytical Reagent for the Determination of Pharmaceutical Amine by Spectrophotometry Abdalla Ahmed Elbashir a , Abir Abdalla Ahmed a , Shazalia M. Ali Ahmed a & Hassan Y. Aboul-Enein b a University of Khartoum, Faculty of Science, Chemistry Department, Khartoum, Sudan b Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical...
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Aim: To develop and validate a sensitive method for the determination of rapeprazole (RPZ) and omeprazole (OPZ) in bulk and formulations based on nucleophilic substitution reaction of RPZ and OPZ with sodium 1,2-naphthoquinone-4-sulphonate (NQS) in an alkaline medium. Study Design: All variables were studied to optimize the reaction conditions and the reaction mechanism was postulated. Place an...
متن کاملSpectrophotometric Determination of Corticosteroids and Its Application in Pharmaceutical Formulation
A simple, sensitive and economically viable spectrophotometric method for the determination of corticosteroids (predinsolone {PSL}, dexamethasone {DEX}, prednisone {PS}, betamethasone sodium phosphate {BEP} and hydrocortisone {HYD} has been developed. The method involves the oxidation of corticosteroids by iron (III) and subsequent complexation of iron (II) with potassium hexacynoferrate (III),...
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ژورنال
عنوان ژورنال: Journal of the Association of Arab Universities for Basic and Applied Sciences
سال: 2012
ISSN: 1815-3852
DOI: 10.1016/j.jaubas.2011.12.003